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Serum soluble sCD is a shedding
2024-08-22

Serum soluble sCD21 is a shedding product from the ectodomain of membrane CD21 after B cell activation (Masilamani et al., 2003, Masilamani et al., 2004a, Masilamani et al., 2004b, Grottenthaler et al., 2006, Hoefer et al., 2008), which resembles the ligand-binding capacity of intact CD21 (Wu et al.
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br Acknowledgments This work was
2024-08-22

Acknowledgments This work was supported by the R&D Program of the Institutional Research Program of KRICT (SI1701-02), and by the Next generation carbon upcycling project of Ministry of Science and ICT. JSC is kindly grateful to the National Research Council of Science and Technology (NST) for fi
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faah inhibitor Finally Urban Ciecko et al asked whether this
2024-08-22

Finally, Urban-Ciecko et al. (2018) asked whether this enhancement is specific to the pyramidal to SST neuron synapses or more generally observed in other synapses of the cortical microcircuit. Synapses between pyramidal cells showed no sign of potentiation after either bath application of the choli
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The role of DHT in early teleost embryogenesis is not
2024-08-22

The role of DHT in early teleost embryogenesis is not entirely clear or established, however additional studies that treat fish embryos to DHT or to specific srd5a inhibitors at critical stages of development (i.e. prior to sex differentiation) will shed light on the early functions of this androgen
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br Conflict of interest br Introduction Ovarian
2024-08-22

Conflict of interest Introduction Ovarian cancer is the most lethal gynecological malignancy, and ranks as the fifth leading cause of cancer death among women. The American Cancer Society estimates that about 22,280 new ovarian cancer cases and 14,240 deaths will occur in the United States in
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Jesus et al discovered a new series of azaindole as
2024-08-22

Jesus et al. discovered a new series of azaindole as Aurora inhibitors through various modification of GSK1070916 (47). They synthesized series from modification of the GSK1070916 and evaluated for in-vitro Aurora-B/INCENP and Aurora-A/TPX2 inhibition assays. Modified Alverine Citrate 48 and 49 sho
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The Limitations of our data include
2024-08-22

The Limitations of our data include the absence of functional/behavioral assessments and lack of direct comparison with females which would require additional studies and conceivably support sex-specific interventions for stroke [50]. Competing interests Acknowledgements This study was suppor
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Phenolic compounds show reciprocal relationship with colonic
2024-08-22

Phenolic compounds show reciprocal relationship with colonic microflora. Phenolic compounds are able to improve colonic health and modulate microbiota diversity with prebiotic and antimicrobial functions, while colonic bacterial enzymes catalyze deconjugation, dehydroxylation, and convert phenolic c
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Protein arrays provide a new approach for
2024-08-22

Protein arrays provide a new approach for the identification of substrates for several protein-modifying enzymes. For example, protein kinase substrate identification, which constitutes an important aspect of pathway mapping because of the prevalence of these substrates in biological pathways. MacBe
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br Introduction Increasing number of mycosis infections has
2024-08-22

Introduction Increasing number of mycosis infections has been reported during the past several years because of the rise in the number of immuno-compromised individuals in subtropical and tropical countries with high mortality and morbidity [1], [2]. Trichophyton mentagrophytes, Trichophyton rubr
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br Experimental Procedures br Acknowledgments br Introductio
2024-08-21

Experimental Procedures Acknowledgments Introduction Cellular and molecular mechanisms underlying synaptic plasticity in the BIX 02565 are thought to be involved in memory acquisition. Synaptic plasticity is categorised into two main types, long-term depression (LTD) and long-term potentiat
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br Results and discussion br Conclusion The tyrosine kinase
2024-08-21

Results and discussion Conclusion The tyrosine kinase ALK represents one of the most successful molecular targets for the development of precise medicine to treat stratified subgroups of cancer patients. Three generations of ALK inhibitors have been awarded the FDA's approval or are being exte
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br Disclosure br Acknowledgments br Introduction Anaplastic
2024-08-21

Disclosure Acknowledgments Introduction Anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase, belongs to the insulin receptor kinase subfamily [1]. Oncogenic activation of ALK is associated with the Manidipine 2HCl and progression of multiple human cancer types [2,3], including ana
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br Conclusion br Conflict of interest br Acknowledgments We
2024-08-21

Conclusion Conflict of interest Acknowledgments We thank Nancy Kerkvliet for helpful advice. The research in the lab of CE and THS is supported by the Deutsche Forschungsgemeinschaft (grants ES103/7-1 and 9-1, HA7346/2-1). We apologize to all authors whose work could not be cited due to lim
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In the current study adiponectin receptors expressions were
2024-08-21

In the current study, adiponectin receptors expressions were detected in both cell lines. AdipoR2 showed equal expression levels, whereas AdipoR1 possessed different expression levels in both cell lines. There was a significant increase in the AdipoR1 mRNA levels in cell lines according to AdipoR2 m
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